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Companies / Health Care / Kyverna Therapeutics, Inc.
KYTX

Kyverna Therapeutics, Inc.

Health CareBiological Products
Ticker KYTXEMERYVILLE, CAFiscal year ends DecemberBook value per share $2.73Diluted shares 60.7M

Kyverna Therapeutics (Nasdaq: KYTX) is a clinical-stage biopharmaceutical company developing cell therapies for autoimmune diseases. Its lead candidate, mivocabtagene autoleucel (miv-cel, also known as KYV-101), is an autologous, fully human CD19-targeting CAR T-cell therapy designed to deplete B cells. Kyverna is… From the company’s description.

In fiscal 2025, Kyverna Therapeutics, Inc. reported a net loss of $161.31M. Operations used $153.71M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-161.31MFY2025
−26.5% year over year
Last 12 mo $-152.64M
-69.45%FY2025
−21.6 percentage points
Last 12 mo -92.20%
Cash & financing
$-153.71MFY2025
−34.5% year over year
Last 12 mo $-158.75M
$-154.84MFY2025
−33.0% year over year
Last 12 mo $-160.23M
0.11FY2025
Was 0.00× a year earlier
Last 12 mo 0.15
44.3MFY2025
+15.5% year over year
Last 12 mo 60.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Kyverna Therapeutics, Inc. does

In the company’s own words

Kyverna Therapeutics (Nasdaq: KYTX) is a clinical-stage biopharmaceutical company developing cell therapies for autoimmune diseases. Its lead candidate, mivocabtagene autoleucel (miv-cel, also known as KYV-101), is an autologous, fully human CD19-targeting CAR T-cell therapy designed to deplete B cells. Kyverna is advancing miv-cel in stiff person syndrome (SPS) and generalized myasthenia gravis (gMG), with additional studies exploring progressive multiple sclerosis, rheumatoid arthritis, lupus nephritis and systemic sclerosis. The company reported positive results from its registrational Phase 2 SPS trial and is preparing a biologics license application; its gMG program includes a Phase 3 trial. Kyverna also develops manufacturing and next-generation CAR T-cell technologies, including KYV-102, a rapid manufacturing process. The company focuses on research and development and reports no business segments in the available business description. Its website is https://www.kyvernatx.com/

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
EMERYVILLE, CA
Fiscal year end
December
CIK
1994702
SIC
2836

Financial performance, year by year

Fiscal 2024–2025 · USD
$-164.69M$-154.54M$-144.39M$-134.24M$-124.09M20242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Kyverna Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

91
funds hold it
0 of 35
superinvestors hold it
$60.85M
held by funds, at market
11.1%
of shares held by funds

Largest fund holders · Kyverna Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
T. Rowe Price Health Sciences Fund, Inc.
PRHSX · T. ROWE PRICE HEALTH SCIENCES FUND, INC.
0.06%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 Value ETF
IWN · iShares Trust
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Kyverna Therapeutics, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Kyverna Therapeutics, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
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