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Companies / Health Care / Lexeo Therapeutics, Inc.
LXEO

Lexeo Therapeutics, Inc.

Health CareBiological Products
Ticker LXEONEW YORK, NYFiscal year ends DecemberBook value per share $2.82Diluted shares 83.4M

Lexeo Therapeutics, Inc. (Nasdaq: LXEO) is a clinical-stage genetic medicine company developing gene therapies for cardiovascular and neurodegenerative diseases. Its cardiovascular portfolio targets genetically defined conditions, including Friedreich ataxia cardiomyopathy, PKP2-related arrhythmogenic cardiomyopathy,… From the company’s description.

In fiscal 2025, Lexeo Therapeutics, Inc. reported a net loss of $99.96M. Operations used $98.56M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-99.96MFY2025
−1.7% year over year
Last 12 mo $-87.27M
-40.52%FY2025
+43.6 percentage points
Last 12 mo -37.12%
Cash & financing
$-98.56MFY2025
−21.5% year over year
Last 12 mo $-88.37M
$-98.96MFY2025
−21.2% year over year
Last 12 mo $-88.70M
0.00FY2025
Was 0.01× a year earlier
Last 12 mo 0.00
53.6MFY2025
+68.8% year over year
Last 12 mo 83.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Lexeo Therapeutics, Inc. does

In the company’s own words

Lexeo Therapeutics, Inc. (Nasdaq: LXEO) is a clinical-stage genetic medicine company developing gene therapies for cardiovascular and neurodegenerative diseases. Its cardiovascular portfolio targets genetically defined conditions, including Friedreich ataxia cardiomyopathy, PKP2-related arrhythmogenic cardiomyopathy, DSP cardiomyopathy, and TNNI3-related hypertrophic cardiomyopathy. The lead candidates, LX2006 and LX2020, are in Phase 1/2 clinical trials; LX2021 and LX2022 are in preclinical development. The company’s candidates are designed to deliver functional genes to address underlying genetic causes, and its most advanced programs use an AAVrh10 vector. Lexeo also develops therapies for APOE4-associated Alzheimer’s disease, including LX1001, which completed a Phase 1/2 trial, and two early-stage candidates. It is seeking business development opportunities for its Alzheimer’s portfolio. Lexeo retains exclusive worldwide development and commercialization rights to its product candidates and programs.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
NEW YORK, NY
Fiscal year end
December
CIK
1907108
SIC
2836

Financial performance, year by year

Fiscal 2023–2025 · USD
$-103.32M$-93.25M$-83.18M$-73.11M$-63.04M202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Lexeo Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

138
funds hold it
0 of 35
superinvestors hold it
$77.09M
held by funds, at market
19.3%
of shares held by funds

Largest fund holders · Lexeo Therapeutics, Inc.’s weight in each

0.11%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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