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Companies / Health Care / Milestone Scientific Inc.
MLSS

Milestone Scientific Inc.

Health CareMedical Instruments
Ticker MLSSLIVINGSTON, NJFiscal year ends DecemberBook value per share $0.04Diluted shares 87.4M

Milestone Scientific Inc. (NYSE American: MLSS) develops and commercializes computer-controlled drug delivery systems for dental and medical procedures. Its proprietary Dynamic Pressure Sensing technology controls injection flow and measures pressure at the needle tip in real time, supporting local anesthesia… From the company’s description.

Over the twelve months to Jun 30, 2026, Milestone Scientific Inc. reported revenue of $9.42M, up 3.7% from a year earlier, and a net loss of $4.14M. Its operating margin was −43.5%, and operations used $0.64M in cash. In fiscal 2025, it reported revenue of $8.97M, up 4.0% from fiscal 2024, and a net loss of $5.72M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$8.97MFY2025
+4.0% year over year
Last 12 mo $9.42M
-63.52%FY2025
+15.3 percentage points
Last 12 mo -43.52%
$-5.72MFY2025
−21.4% year over year
Last 12 mo $-4.14M
-203.45%FY2025
−122.6 percentage points
Last 12 mo -119.36%
Cash & financing
$-2.92MFY2025
+0.1% year over year
Last 12 mo $-0.64M
$-2.93MFY2025
−0.4% year over year
Last 12 mo $-0.64M
0.30FY2025
Was 0.01× a year earlier
Last 12 mo 0.15
82.1MFY2025
Last 12 mo 87.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Milestone Scientific Inc. does

In the company’s own words

Milestone Scientific Inc. (NYSE American: MLSS) develops and commercializes computer-controlled drug delivery systems for dental and medical procedures. Its proprietary Dynamic Pressure Sensing technology controls injection flow and measures pressure at the needle tip in real time, supporting local anesthesia delivery, epidural placement, and joint injections. Dental products include the CompuDent and STA Single Tooth Anesthesia systems, used with disposable Wand handpieces and sold through online sales and distributors. Medical products include the CompuFlo Epidural System, which provides clinicians with pressure feedback to help identify the epidural space. The company sells to dental offices and groups, as well as healthcare providers, through direct sales, e-commerce, and third-party distributors in domestic and international markets. It operates in dental and medical product markets and reports approximately 45% of 2025 sales outside the United States; its products are sold in about 37 countries and U.S. territories. Milestone Scientific held approximately 305 issued U.S. and foreign patents. Its website is www.milestonescientific.com.

Company details
Sector
Health Care
Industry (SIC)
Medical Instruments
Headquarters
LIVINGSTON, NJ
Fiscal year end
December
CIK
855683
SIC
3842

Financial performance, year by year

Fiscal 2012–2025 · USD
$-10.78M$-4.76M$1.25M$7.27M$13.29M20122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Milestone Scientific Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

7
funds hold it
0 of 35
superinvestors hold it
$0.89M
held by funds, at market
3.0%
of shares held by funds

Largest fund holders · Milestone Scientific Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
—of fund net assets
Ultra-Small Company Market Fund
BRSIX · Bridgeway Funds, Inc.
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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