MILESTONE SCIENTIFIC INC.

Milestone Scientific Inc. (NYSE American: MLSS) develops and commercializes proprietary computer-controlled drug delivery systems designed to enhance the safety, precision, and patient experience associated with subcutaneous injections and fluid aspiration procedures. The company's website is www.milestonescientific.com.

The company's core technology platform, Dynamic Pressure Sensing (DPS) Technology, controls flow rate and measures pressure at the needle tip in real time. This technology is incorporated into both dental and medical products supporting clinical applications including local anesthesia delivery, epidural space identification in regional anesthesia procedures, and intra-articular joint injections.

In the dental market, Milestone Scientific markets products under the CompuDent and STA Single Tooth Anesthesia System trademarks utilizing The Wand, a single-use disposable handpiece. These products are sold in the United States, Canada, and more than 40 other countries. The STA System has been used to administer more than 95 million injections globally since its commercial introduction in 2007. In the medical market, the company has received FDA 510(k) clearance for its CompuFlo Epidural Computer Controlled Anesthesia System for use in specified regions of the spine, with expanded clearance in 2023 for thoracic region use.

The company holds approximately 305 issued U.S. and foreign patents along with numerous pending applications, and maintains approximately 10 registered U.S. and foreign trademarks. Milestone Scientific relies on third-party manufacturers for product production, with dental handpieces sourced from a China-based manufacturer and the Wand/STA System and epidural devices manufactured by a U.S.-based supplier.

As of the most recent reporting period, the company employed 15 full-time employees. In 2025, export sales outside the United States represented approximately 45 percent of total sales, with products sold in approximately 37 countries and U.S. territories. The company markets dental products through e-commerce and exclusive distribution arrangements internationally, while medical products are sold through direct sales and third-party distribution arrangements in both domestic and international markets.