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Companies / Healthcare / OMEROS CORP
OMER

OMEROS CORP

HealthcarePharmaceutical Preparations
Ticker OMERSEATTLE, WAFiscal year ends DecemberBook value per share $-0.57Diluted shares 89.9M

Omeros Corporation (NASDAQ: OMER) is a biopharmaceutical company engaged in the development and commercialization of pharmaceutical products, with a primary focus on compounds and therapies directed toward complement pathway targets and alternative pathway mechanisms. The company's website is www.omeros.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%
$-3.35M
+97.9% year over year
Last 12 mo $124.83M
2.76%
−83.1 percentage points
Last 12 mo -243.09%
Cash & financing
$-116.09M
+22.0% year over year
Last 12 mo $-68.67M
$-116.16M
+22.0% year over year
Last 12 mo $-68.73M
-0.56
Was -1.03× a year earlier
Last 12 mo -0.82
67.0M
Last 12 mo 89.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What OMEROS CORP does

In the company’s own words

Omeros Corporation (NASDAQ: OMER) is a biopharmaceutical company engaged in the development and commercialization of pharmaceutical products, with a primary focus on compounds and therapies directed toward complement pathway targets and alternative pathway mechanisms. The company's website is www.omeros.com.

The company operates through a single reportable segment focused on the development and commercialization of its proprietary pharmaceutical pipeline. Omeros' core business involves the research, development, manufacturing, and commercialization of innovative drug candidates, with particular emphasis on monoclonal antibodies and small molecules targeting specific biological pathways relevant to serious diseases.

The company's primary asset is its Compound, referred to as zaltenibart or OMS906, which is a monoclonal antibody targeting MASP-3 (mannan-binding lectin-associated serine protease-3). This compound and related products represent the foundation of Omeros' clinical development programs and commercial strategy. The company has established intellectual property portfolios across multiple patent families covering various aspects of its therapeutic approaches and manufacturing processes.

Omeros maintains operations across multiple geographic markets and collaborates with contract manufacturers and research organizations to support its development and manufacturing activities. The company's business model centers on advancing its proprietary compounds through clinical development stages toward regulatory approval and eventual commercialization, while also exploring licensing and partnership opportunities to expand its reach and capabilities.

In October 2025, Omeros entered into a significant asset purchase and license agreement with Novo Nordisk Health Care AG, whereby Novo Nordisk acquired certain assets related to Omeros' programs, including intellectual property, regulatory submissions, manufacturing technology, and related materials. Under this transaction structure, Omeros retained certain rights through exclusive and non-exclusive licenses to background technology and know-how, positioning the company to continue participating in the development and commercialization of products derived from its research while leveraging Novo Nordisk's resources and commercial capabilities.

Company details
Sector
Healthcare
Industry
Pharmaceutical Preparations
Headquarters
SEATTLE, WA
Fiscal year end
December
CIK
1285819
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-191.92M$-86.61M$18.71M$124.03M$229.34M2013201420152016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns OMEROS CORP — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

133
funds hold it
0 of 35
superinvestors hold it
$118.59M
held by funds, at market
15.8%
of shares held by funds

Largest fund holders · OMEROS CORP’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.02%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
0.03%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.01%of fund net assets
1.42%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do OMEROS CORP and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of OMEROS CORP's earnings go — cash, debt, buybacks, reinvestment?”
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