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Companies / Health Care / Organogenesis Holdings Inc.
ORGO

Organogenesis Holdings Inc.

Health CarePharmaceutical Preparations
Ticker ORGOCANTON, MAFiscal year ends DecemberBook value per share $1.16Diluted shares 128.2M

Organogenesis Holdings Inc. (Nasdaq: ORGO) is a leading regenerative medicine company focused on developing, manufacturing, and commercializing advanced wound care and surgical and sports medicine products. The company's mission centers on advancing healing and recovery through innovative biologic solutions that… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$564.17M
+17.0% year over year
Last 12 mo $457.45M
7.92%
+8.2 percentage points
Last 12 mo -7.84%
$37.03M
+4201.0% year over year
Last 12 mo $-84.16M
12.34%
+12 percentage points
Last 12 mo -56.76%
Cash & financing
$-10.31M
−172.6% year over year
Last 12 mo $31.97M
$-24.46M
−685.7% year over year
Last 12 mo $20.84M
0.07
Was 0.01× a year earlier
Last 12 mo 0.08
130.2M
−1.1% year over year
Last 12 mo 128.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Organogenesis Holdings Inc. does

In the company’s own words

Organogenesis Holdings Inc. (Nasdaq: ORGO) is a leading regenerative medicine company focused on developing, manufacturing, and commercializing advanced wound care and surgical and sports medicine products. The company's mission centers on advancing healing and recovery through innovative biologic solutions that address large and growing markets driven by aging demographics and increasing prevalence of comorbidities such as diabetes, obesity, and cardiovascular disease.

The company operates primarily through two market segments: Advanced Wound Care and Surgical & Sports Medicine. In Advanced Wound Care, Organogenesis offers a comprehensive portfolio including Apligraf, a bioengineered bi-layered skin substitute approved for treating venous leg ulcers and diabetic foot ulcers; Dermagraft, a dermal substitute for diabetic foot ulcers; and multiple placental-based products including Affinity, Novachor, and NuShield. The company also markets PuraPly Antimicrobial and related collagen-based products, along with CYGNUS Dual, VIA Matrix, and SimpliMax for various wound types. In Surgical & Sports Medicine, Organogenesis leverages its regenerative medicine capabilities to address surgical wounds and musculoskeletal injuries, with products including NuShield, CYGNUS Matrix, PuraForce, and Affinity for soft tissue repair applications.

Organogenesis sells its products throughout the United States via a direct sales force comprising 224 representatives as of December 31, 2025, supplemented by approximately 175 independent agencies. The company maintains commercial operations in select international markets including Switzerland, Saudi Arabia, Kuwait, and Mexico. The company manufactures its primary non-placental products in-house and utilizes third-party manufacturers for placental-based products. Organogenesis operates research and development facilities in Canton, Massachusetts; Birmingham, Alabama; and San Diego, California, where its internal team develops the majority of its product portfolio.

The company's pipeline includes line extensions for existing products, new placental-based formulations, FortiShield for burn treatment, TransCyte for deep burns, and ReNu, a cryopreserved amniotic suspension for osteoarthritis management currently in regulatory review. Organogenesis has demonstrated its acquisition capability through strategic purchases including Dermagraft and TransCyte from Shire and placental-based products from NuTech Medical in 2017. The company is constructing a state-of-the-art biomanufacturing facility in Smithfield, Rhode Island, expected to commence operations in 2027.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CANTON, MA
Fiscal year end
December
CIK
1661181
SIC
2834

Financial performance, year by year

Fiscal 2016–2025 · USD
$-148.99M$45.51M$240.01M$434.50M$629.00M2016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Organogenesis Holdings Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

148
funds hold it
0 of 35
superinvestors hold it
$36.35M
held by funds, at market
11.6%
of shares held by funds

Largest fund holders · Organogenesis Holdings Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
0.00%of fund net assets
iShares Russell 2000 Value ETF
IWN · iShares Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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