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Companies / Health Care / OS Therapies Inc
OSTX

OS Therapies Inc

Health CarePharmaceutical Preparations
Ticker OSTXROCKVILLE, MDFiscal year ends DecemberBook value per share $-0.29Diluted shares 41.4M

OS Therapies Incorporated (NYSE: OSTX) is a clinical-stage biopharmaceutical company developing treatments for osteosarcoma and other solid tumors. Its lead candidate, OST-HER2, is an off-the-shelf immunotherapy made from an attenuated, genetically modified Listeria strain that expresses HER2 peptides and is intended… From the company’s description.

In fiscal 2025, OS Therapies Inc reported a net loss of $28.75M. Operations used $14.24M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-28.75MFY2025
−223.7% year over year
Last 12 mo $-39.37M
472.47%FY2025
+302.9 percentage points
Last 12 mo 330.81%
Cash & financing
$-14.24MFY2025
−95.5% year over year
Last 12 mo $-18.53M
$-14.70MFY2025
−101.9% year over year
Last 12 mo $-18.53M
—
Was 0.00× a year earlier
29.3MFY2025
+136.5% year over year
Last 12 mo 41.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What OS Therapies Inc does

In the company’s own words

OS Therapies Incorporated (NYSE: OSTX) is a clinical-stage biopharmaceutical company developing treatments for osteosarcoma and other solid tumors. Its lead candidate, OST-HER2, is an off-the-shelf immunotherapy made from an attenuated, genetically modified Listeria strain that expresses HER2 peptides and is intended to stimulate an immune response against cancer. The company’s Phase IIb study evaluated OST-HER2 in patients after surgery for recurrent pulmonary metastatic osteosarcoma and enrolled 41 patients. Its second technology, OST-tADC, is a preclinical antibody-drug conjugate platform using pH-sensitive silicon linkers to deliver payloads to tumors; its lead program targets folate receptor alpha, which is overexpressed in several cancers. OS Therapies acquired HER2-related assets from Ayala Pharmaceuticals in 2025, including investigational programs for non-small cell lung and prostate cancers. The company has no approved commercial products and relies on third parties for manufacturing. Its website is www.ostherapies.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
ROCKVILLE, MD
Fiscal year end
December
CIK
1795091
SIC
2834

Financial performance, year by year

Fiscal 2024–2025 · USD
$-42.42M$-33.27M$-24.13M$-14.98M$-5.83M20242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns OS Therapies Inc — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

8
funds hold it
0 of 35
superinvestors hold it
$2.24M
held by funds, at market
2.5%
of shares held by funds

Largest fund holders · OS Therapies Inc’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.01%of fund net assets
Ultra-Small Company Market Fund
BRSIX · Bridgeway Funds, Inc.
0.06%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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