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Companies / Health Care / Pelthos Therapeutics Inc.
PTHS

Pelthos Therapeutics Inc.

Health CareBiological Products
Ticker PTHSDURHAM, NCFiscal year ends DecemberBook value per share $-0.44Diluted shares 3.4M

Pelthos Therapeutics Inc. (NYSE: PTHS) is a biopharmaceutical company commercializing prescription products and developing potential therapies for skin conditions and pain. Its commercial portfolio includes ZELSUVMI, a topical gel for molluscum contagiosum launched in the United States in July 2025; XEPI, a cream for… From the company’s description.

In fiscal 2025, Pelthos Therapeutics Inc. reported revenue of $16.80M and a net loss of $43.32M. Its operating margin was −193.1%, and operations used $22.59M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$16.80MFY2025
-193.09%FY2025
$-43.32MFY2025
−444.6% year over year
Last 12 mo $-86.39M
-111.41%FY2025
−404.5 percentage points
Last 12 mo 5755.63%
Cash & financing
$-22.59MFY2025
−290.0% year over year
Last 12 mo $-42.30M
$-22.69MFY2025
−291.7% year over year
Last 12 mo $-42.30M
0.81FY2025
Was -0.81× a year earlier
Last 12 mo -46.58
1.9MFY2025
+237.3% year over year
Last 12 mo 3.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Pelthos Therapeutics Inc. does

In the company’s own words

Pelthos Therapeutics Inc. (NYSE: PTHS) is a biopharmaceutical company commercializing prescription products and developing potential therapies for skin conditions and pain. Its commercial portfolio includes ZELSUVMI, a topical gel for molluscum contagiosum launched in the United States in July 2025; XEPI, a cream for impetigo; and XEGLYZE, a treatment for head lice. The latter two products were acquired in 2025, with relaunch and launch activities planned, respectively. Pelthos markets ZELSUVMI to pediatricians, pediatric dermatologists and dermatologists, distributing it through retail and mail-order pharmacies and Amazon Pharmacy. The company also has clinical-stage programs targeting the NaV1.7 sodium channel for eye, postoperative and neuropathic pain, and manufactures berdazimer sodium, the active ingredient in ZELSUVMI, at its North Carolina facility. Pelthos was formed in July 2025 through the merger of Channel Therapeutics and LNHC, bringing together commercial products, manufacturing capabilities and pain-development assets. Its website is www.pelthostherapeutics.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
DURHAM, NC
Fiscal year end
December
CIK
1919246
SIC
2836

Financial performance, year by year

Fiscal 2023–2025 · USD
$-96.71M$-65.75M$-34.80M$-3.84M$27.11M202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Pelthos Therapeutics Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

9
funds hold it
0 of 35
superinvestors hold it
$3.20M
held by funds, at market
3.0%
of shares held by funds

Largest fund holders · Pelthos Therapeutics Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.01%of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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