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Companies / Health Care / Q32 Bio Inc.
QTTB

Q32 Bio Inc.

Health CarePharmaceutical Preparations
Ticker QTTBWALTHAM, MAFiscal year ends DecemberBook value per share $12.55Diluted shares 22.9M

Q32 Bio (Nasdaq: QTTB) is a clinical-stage biotechnology company developing biologics for autoimmune and inflammatory diseases. Its lead candidate, bempikibart, is a fully human monoclonal antibody designed to block IL-7 and TSLP signaling, and is being evaluated for severe and very severe alopecia areata, a disease… From the company’s description.

In fiscal 2025, Q32 Bio Inc. reported revenue of $53.74M and net income of $29.82M. Its operating margin was 31.5%, and operations used $33.54M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$53.74MFY2025
31.45%FY2025
$29.82MFY2025
+162.5% year over year
Last 12 mo $32.25M
70.98%FY2025
+912.1 percentage points
Last 12 mo 11.21%
Cash & financing
$-33.54MFY2025
+50.5% year over year
Last 12 mo $-20.02M
$-33.54MFY2025
+50.5% year over year
Last 12 mo $-20.07M
0.23FY2025
Was 2.23× a year earlier
Last 12 mo 0.00
12.3MFY2025
+27.5% year over year
Last 12 mo 22.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Q32 Bio Inc. does

In the company’s own words

Q32 Bio (Nasdaq: QTTB) is a clinical-stage biotechnology company developing biologics for autoimmune and inflammatory diseases. Its lead candidate, bempikibart, is a fully human monoclonal antibody designed to block IL-7 and TSLP signaling, and is being evaluated for severe and very severe alopecia areata, a disease that causes hair loss. The company completed Phase 2a trials in alopecia areata and atopic dermatitis and is conducting an open-label Phase 2a trial in alopecia areata; 33 patients enrolled in that trial, with dosing ongoing at year-end 2025. Q32 Bio has no products for sale and has not generated product revenue. It sold substantially all assets related to its ADX-097 complement-inhibitor program to Akebia Therapeutics in November 2025, while retaining rights to ADX-096 and other early-stage assets from its tissue-targeted complement-inhibitor platform. Its operations are focused on advancing bempikibart and evaluating options for the retained platform.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
WALTHAM, MA
Fiscal year end
December
CIK
1661998
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-146.94M$-92.21M$-37.48M$17.25M$71.98M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Q32 Bio Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

25
funds hold it
0 of 35
superinvestors hold it
$9.86M
held by funds, at market
2.7%
of shares held by funds

Largest fund holders · Q32 Bio Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Avantis U.S. Small Cap Value ETF
AVUV · American Century ETF Trust
—of fund net assets
Ultra-Small Company Fund
BRUSX · Bridgeway Funds, Inc.
0.45%of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.02%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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