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Companies / Health Care / Rani Therapeutics Holdings, Inc.
RANI

Rani Therapeutics Holdings, Inc.

Health CarePharmaceutical Preparations
Ticker RANISAN JOSE, CAFiscal year ends DecemberBook value per share $0.22Diluted shares 180.0M

Rani Therapeutics Holdings, Inc. (NASDAQ: RANI) is a clinical-stage biopharmaceutical company developing proprietary oral delivery technologies for biologics and drugs. The company's website is www.ranitherapeutics.com. From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$1.63M
+58.9% year over year
Last 12 mo $4.88M
-2345.99%
+2840.2 percentage points
Last 12 mo -675.80%
$-40.95M
+27.6% year over year
Last 12 mo $-33.42M
-89.89%
+1417 percentage points
Last 12 mo -76.82%
Cash & financing
$-18.71M
+47.3% year over year
Last 12 mo $-20.29M
$-18.80M
+47.4% year over year
Last 12 mo $-20.34M
0.00
Was 12.36× a year earlier
66.1K
+132.3% year over year
Last 12 mo 180.0M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Rani Therapeutics Holdings, Inc. does

In the company’s own words

Rani Therapeutics Holdings, Inc. (NASDAQ: RANI) is a clinical-stage biopharmaceutical company developing proprietary oral delivery technologies for biologics and drugs. The company's website is www.ranitherapeutics.com.

Rani operates through its consolidated subsidiary, Rani Therapeutics, LLC, and focuses on advancing a drug-agnostic oral delivery platform called the RaniPill capsule, designed to deliver a wide variety of drug substances including antibodies, proteins, peptides, and oligonucleotides. The company has developed two configurations of its platform: the RaniPill GO, designed to deliver up to three milligrams of drug in microtablet form with high bioavailability, and the RaniPill HC, a high-capacity version intended to enable delivery of drug payloads up to two hundred microliters in liquid form.

The RaniPill capsule operates as an orally ingestible pill approximately the size of a standard fish oil or calcium supplement. It features a proprietary pH-sensitive coating that protects the drug through the stomach's acidic environment and deploys in the jejunum portion of the small intestine. Upon deployment, a self-inflating balloon orients a microneedle approximately perpendicular to the intestinal wall, delivering the drug payload directly into the highly vascularized intestinal tissue for absorption into the bloodstream.

Rani's pipeline includes multiple product candidates in various development stages. RT-114, a RaniPill HC capsule containing a GLP-1/GLP-2 dual agonist for obesity treatment, initiated Phase 1 clinical trials in December 2025. RT-116 contains semaglutide for obesity treatment and is in preclinical development. RT-111, containing an ustekinumab biosimilar for inflammatory conditions, completed a Phase 1 study. RT-105, an adalimumab biosimilar for psoriatic arthritis, is paused pending strategic review. RT-117, developed through a collaboration with Chugai Pharmaceutical for hemophilia treatment, represents a partnered program.

The company has established strategic collaborations, including a partnership with Chugai Pharmaceutical and ProGen Co., Ltd. Rani maintains vertically integrated manufacturing capabilities and plans to continue scaling and optimizing manufacturing processes through expanded automation. The company has not generated revenue from commercial products and remains in early clinical development stages with no approved products.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
SAN JOSE, CA
Fiscal year end
December
CIK
1856725
SIC
2834

Financial performance, year by year

Fiscal 2021–2025 · USD
$-75.16M$-53.33M$-31.50M$-9.68M$12.15M20212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Rani Therapeutics Holdings, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

13
funds hold it
0 of 35
superinvestors hold it
$4.26M
held by funds, at market
4.7%
of shares held by funds

Largest fund holders · Rani Therapeutics Holdings, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
0.00%of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
0.00%of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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