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Companies / Health Care / Sarepta Therapeutics, Inc.
SRPT

Sarepta Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker SRPTCAMBRIDGE, MAFiscal year ends DecemberBook value per share $14.20Diluted shares 107.6M

Sarepta Therapeutics, Inc. (Nasdaq: SRPT) is a commercial-stage biopharmaceutical company developing and selling genetic medicines for rare diseases, with a focus on Duchenne muscular dystrophy and other neuromuscular disorders. Its approved Duchenne products are EXONDYS 51, VYONDYS 53 and AMONDYS 45, which use… From the company’s description.

Over the twelve months to Sep 30, 2026, Sarepta Therapeutics, Inc. reported revenue of $1.96B, down 18.9% from a year earlier, and net income of $14.76M. Its operating margin was −2.5%, and operations generated $185.56M in cash. In fiscal 2025, it reported revenue of $2.20B, up 15.6% from fiscal 2024, and a net loss of $713.41M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$2.20BFY2025
+15.6% year over year
Last 12 mo $1.96B
-31.83%FY2025
−43.3 percentage points
Last 12 mo -2.50%
$-713.41MFY2025
−403.3% year over year
Last 12 mo $14.76M
-58.92%FY2025
−74.3 percentage points
Last 12 mo 1.00%
Cash & financing
$-205.48MFY2025
+0.1% year over year
Last 12 mo $185.56M
$-307.45MFY2025
+10.3% year over year
Last 12 mo $176.40M
0.73FY2025
Was 0.74× a year earlier
Last 12 mo 0.56
100.1MFY2025
−7.2% year over year
Last 12 mo 107.6M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Sarepta Therapeutics, Inc. does

In the company’s own words

Sarepta Therapeutics, Inc. (Nasdaq: SRPT) is a commercial-stage biopharmaceutical company developing and selling genetic medicines for rare diseases, with a focus on Duchenne muscular dystrophy and other neuromuscular disorders. Its approved Duchenne products are EXONDYS 51, VYONDYS 53 and AMONDYS 45, which use exon-skipping technology, and ELEVIDYS, an AAV-based gene therapy. Sarepta is also developing gene therapy and siRNA candidates for conditions including limb-girdle muscular dystrophy, facioscapulohumeral muscular dystrophy and myotonic dystrophy type 1, including siRNA programs partnered with Arrowhead. It commercializes its products through specialty pharmacies, distributors and hospital channels, and collaborates with Roche on ELEVIDYS outside the United States. The company reports a single operating segment and recorded $1.86 billion in product revenue for fiscal 2025. Its website is www.sarepta.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
873303
SIC
2834

Financial performance, year by year

Fiscal 2011–2025 · USD
$-1.01B$-132.41M$741.58M$1.62B$2.49B201120122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Sarepta Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

304
funds hold it
0 of 35
superinvestors hold it
$869.40M
held by funds, at market
44.4%
of shares held by funds
2
bond issues held by funds

Largest fund holders · Sarepta Therapeutics, Inc.’s weight in each

iShares Core S&P Small-Cap ETF
IJR · iShares Trust
0.10%of fund net assets
0.75%of fund net assets
First Trust NYSE Arca Biotechnology Index Fund
FBT · First Trust Exchange-Traded Fund
2.29%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.06%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Sarepta Therapeutics, Inc.’s bonds, as funds hold them

Funds report holding 2 issues of Sarepta Therapeutics, Inc.’s debt, $64.54M at market value — what funds hold, not the company’s total debt. Weighted-average coupon 3.97%, maturing 2027 to 2030.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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