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Companies / Health Care / Scholar Rock Holding Corp
SRRK

Scholar Rock Holding Corp

Health CareBiological Products
Ticker SRRKCAMBRIDGE, MAFiscal year ends DecemberBook value per share $1.97Diluted shares 129.0M

Scholar Rock (Nasdaq: SRRK) is a global biopharmaceutical company developing therapies for spinal muscular atrophy (SMA) and other rare, severe neuromuscular diseases. Its proprietary platform generates monoclonal antibodies that selectively target inactive precursor forms of growth factors. The lead candidate,… From the company’s description.

In fiscal 2025, Scholar Rock Holding Corp reported a net loss of $377.94M. Operations used $300.04M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-377.94MFY2025
−53.5% year over year
Last 12 mo $-408.59M
-153.95%FY2025
−87.1 percentage points
Last 12 mo -161.00%
Cash & financing
$-300.04MFY2025
−49.3% year over year
Last 12 mo $-296.83M
$-300.64MFY2025
−49.5% year over year
Last 12 mo $-297.01M
0.41FY2025
Was 0.14× a year earlier
Last 12 mo 0.77
114.7MFY2025
+14.9% year over year
Last 12 mo 129.0M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Scholar Rock Holding Corp does

In the company’s own words

Scholar Rock (Nasdaq: SRRK) is a global biopharmaceutical company developing therapies for spinal muscular atrophy (SMA) and other rare, severe neuromuscular diseases. Its proprietary platform generates monoclonal antibodies that selectively target inactive precursor forms of growth factors. The lead candidate, apitegromab, is an investigational anti-myostatin antibody being developed for children and adults with SMA and for people with facioscapulohumeral muscular dystrophy; the company is also developing a subcutaneous formulation and advancing SRK-439, another anti-myostatin antibody. Its early-stage programs include candidates for cancer, fibrotic diseases and iron-restricted anemia, for which it is seeking partners. Scholar Rock is preparing for potential commercialization of apitegromab and has established a U.S. customer-facing team of approximately 50 professionals, with European commercial development beginning in Germany. The company was founded by scientists whose discoveries underpin its platform. Its website is https://scholarrock.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1727196
SIC
2836

Financial performance, year by year

Fiscal 2018–2025 · USD
$-452.77M$-320.23M$-187.70M$-55.16M$77.37M20182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Scholar Rock Holding Corp — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

292
funds hold it
1 of 35
superinvestors hold it
$2.59B
held by funds, at market
41.1%
of shares held by funds

Superinvestors in Scholar Rock Holding Corp · what they did last quarter

Polen CapitalINCREASED +0.3%
Polen Capital Management
<0.1%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Scholar Rock Holding Corp’s weight in each

Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.01%of fund net assets
VANGUARD HEALTH CARE FUND
VGHCX · VANGUARD SPECIALIZED FUNDS
—of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.19%of fund net assets
T. Rowe Price New Horizons Fund, Inc.
PRNHX · T. ROWE PRICE NEW HORIZONS FUND, INC.
0.86%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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