10x Insights
Loading account…
Companies / Health Care / Semnur Pharmaceuticals, Inc.
SMNR

Semnur Pharmaceuticals, Inc.

Health CarePharmaceutical Preparations
Ticker SMNRPALO ALTO, CAFiscal year ends DecemberBook value per share $-0.15Diluted shares 228.2M

Semnur Pharmaceuticals, Inc. (OTC: SMNR) is a late-stage clinical biopharmaceutical company developing non-opioid treatments for acute and chronic pain, with a focus on patients whose needs are not adequately addressed by existing therapies. Its lead candidate, SP-102, is a viscous gel formulation of dexamethasone… From the company’s description.

In fiscal 2025, Semnur Pharmaceuticals, Inc. reported a net loss of $160.42M. Operations used $5.87M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-160.42MFY2025
−95781.8% year over year
Last 12 mo $-18.71M
773.09%FY2025
+771.5 percentage points
Last 12 mo 56.19%
Cash & financing
$-5.87MFY2025
−678.8% year over year
Last 12 mo $-10.63M
$-5.87MFY2025
−678.8% year over year
Last 12 mo $-10.63M
-0.74FY2025
Was -0.14× a year earlier
Last 12 mo -0.79
204.8MFY2025
+7421.6% year over year
Last 12 mo 228.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Semnur Pharmaceuticals, Inc. does

In the company’s own words

Semnur Pharmaceuticals, Inc. (OTC: SMNR) is a late-stage clinical biopharmaceutical company developing non-opioid treatments for acute and chronic pain, with a focus on patients whose needs are not adequately addressed by existing therapies. Its lead candidate, SP-102, is a viscous gel formulation of dexamethasone sodium phosphate being developed as an epidural injection for sciatica, also known as lumbosacral radiculopathy; the product is not yet approved. Semnur completed one Phase 3 study and initiated a second Phase 3 trial in 2025, with development aimed at a potential U.S. regulatory submission. The company has no reportable business segments described; its operations center on SP-102, and it plans to evaluate additional non-opioid pain therapies. Semnur was founded in 2013, acquired by Scilex in 2019, and became a public company following its 2025 business combination with Denali Capital Acquisition Corp. It uses Scilex’s commercial and administrative infrastructure under a transition services agreement. As of December 31, 2025, it had 12 contractors and consultants and three Scilex employees dedicated to SP-102.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
PALO ALTO, CA
Fiscal year end
December
CIK
1913577
SIC
2834

Financial performance, year by year

Fiscal 2022–2025 · USD
$-176.52M$-128.21M$-79.89M$-31.58M$16.74M2022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Semnur Pharmaceuticals, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

7
funds hold it
0 of 35
superinvestors hold it
$0.11M
held by funds, at market
0.1%
of shares held by funds

Largest fund holders · Semnur Pharmaceuticals, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD BALANCED INDEX FUND
VBINX · VANGUARD VALLEY FORGE FUNDS
0.00%of fund net assets
T. Rowe Price Extended Equity Market Index Fund
PEXMX · T. ROWE PRICE INDEX TRUST, INC.
0.00%of fund net assets
VANGUARD INSTITUTIONAL TOTAL STOCK MARKET INDEX FUND
VITNX · VANGUARD INSTITUTIONAL INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

Compare this company with peers, find it in your funds and follow its financial history with your connected AI:

  • “How do Semnur Pharmaceuticals, Inc. and its peers compare on margins and cash generation over ten years?”
  • “Where did five years of Semnur Pharmaceuticals, Inc.'s earnings go — cash, debt, buybacks, reinvestment?”
  • “What changed in Semnur Pharmaceuticals, Inc.'s last four quarterly filings that the numbers alone won't show?”
See how it works →All research tools with a subscription. Use your own AI account.