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Companies / Health Care / Seres Therapeutics, Inc.
MCRB

Seres Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker MCRBCAMBRIDGE, MAFiscal year ends DecemberBook value per share $2.19Diluted shares 9.8M

Seres Therapeutics, Inc. (Nasdaq: MCRB) is a clinical-stage biotechnology company developing oral live biotherapeutic products (LBPs), or bacterial consortia, for medically vulnerable patients and people with inflammatory and immune diseases. Its pipeline includes SER-155, being evaluated for immune checkpoint-related… From the company’s description.

In fiscal 2025, Seres Therapeutics, Inc. reported revenue of $0.79M and net income of $5.70M. Operations generated $1.12M in cash. Over the twelve months to Sep 30, 2026, revenue was $2.13M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$0.79MFY2025
Last 12 mo $2.13M
-11910.14%FY2025
Last 12 mo -3656.89%
$5.70MFY2025
+4088.2% year over year
Last 12 mo $-46.95M
12.88%FY2025
+11.9 percentage points
Last 12 mo -219.83%
Cash & financing
$1.12MFY2025
+100.8% year over year
Last 12 mo $-63.94M
$0.86MFY2025
+100.6% year over year
Last 12 mo $-63.97M
—
8.9MFY2025
+14.2% year over year
Last 12 mo 9.8M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Seres Therapeutics, Inc. does

In the company’s own words

Seres Therapeutics, Inc. (Nasdaq: MCRB) is a clinical-stage biotechnology company developing oral live biotherapeutic products (LBPs), or bacterial consortia, for medically vulnerable patients and people with inflammatory and immune diseases. Its pipeline includes SER-155, being evaluated for immune checkpoint-related enterocolitis and developed to prevent infections in patients undergoing allogeneic stem cell transplantation; SER-603, in preclinical development for inflammatory bowel disease, including ulcerative colitis and Crohn’s disease; and SER-147, designed to prevent infections in patients with metabolic disease. The company uses a microbiome discovery and development platform combining human data, microbial strain libraries, screening and analytics, and maintains manufacturing capabilities for LBPs. Seres led the development of VOWST, the first FDA-approved orally administered microbiome therapeutic, and sold it to Nestlé Health Science in September 2024. The company reports one headline scale metric: research and development operations span clinical studies and proprietary manufacturing capabilities. Its website is https://www.serestherapeutics.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CAMBRIDGE, MA
Fiscal year end
December
CIK
1609809
SIC
2834

Financial performance, year by year

Fiscal 2015–2025 · USD
$-289.67M$-171.14M$-52.62M$65.91M$184.44M20152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Seres Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

24
funds hold it
0 of 35
superinvestors hold it
$3.83M
held by funds, at market
4.9%
of shares held by funds

Largest fund holders · Seres Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Avantis U.S. Small Cap Value ETF
AVUV · American Century ETF Trust
—of fund net assets
Schwab U.S. Small-Cap ETF
SCHA · SCHWAB STRATEGIC TRUST
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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