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Companies / Health Care / Serina Therapeutics, Inc.
SER

Serina Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker SERHUNTSVILLE, ALFiscal year ends DecemberBook value per share $1.32Diluted shares 14.2M

Serina Therapeutics, Inc. (NYSE: SER) is a clinical-stage biotechnology company developing drug candidates that use its proprietary poly(2-oxazoline), or POZ, polymer delivery technology. POZ is designed to modify small molecules, RNA-based therapeutics and antibody-drug conjugates to control drug loading and release;… From the company’s description.

Over the twelve months to Jun 30, 2026, Serina Therapeutics, Inc. reported a net loss of $21.18M. Operations used $21.14M in cash. In fiscal 2025, it reported revenue of $0.13M, up 132.1% from fiscal 2024, and a net loss of $19.21M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$0.13MFY2025
+132.1% year over year
Last 12 mo $0.00M
-18478.46%FY2025
+11964.4 percentage points
$-19.21MFY2025
−71.5% year over year
Last 12 mo $-21.18M
51843.24%FY2025
+53581.3 percentage points
Last 12 mo -113.05%
Cash & financing
$-17.95MFY2025
−4.8% year over year
Last 12 mo $-21.14M
$-18.01MFY2025
−5.0% year over year
Last 12 mo $-21.20M
-79.62FY2025
Was 0.00× a year earlier
Last 12 mo 0.16
10.2MFY2025
+38.5% year over year
Last 12 mo 14.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Serina Therapeutics, Inc. does

In the company’s own words

Serina Therapeutics, Inc. (NYSE: SER) is a clinical-stage biotechnology company developing drug candidates that use its proprietary poly(2-oxazoline), or POZ, polymer delivery technology. POZ is designed to modify small molecules, RNA-based therapeutics and antibody-drug conjugates to control drug loading and release; the company’s candidates target neurological diseases, particularly Parkinson’s disease. Its lead candidate, SER 252, is a POZ-apomorphine conjugate being studied for advanced Parkinson’s disease and designed for long-acting subcutaneous administration; the company began a Phase 1b trial in February 2026. SER 214, a POZ-rotigotine candidate, completed a Phase 1a study and is not being advanced internally. Serina is also conducting preclinical work on POZ lipids for lipid nanoparticle delivery of RNA and licenses its POZ technology to partners, including Pfizer for a specific lipid nanoparticle application. Its business is organized around research and development of its pipeline and platform rather than reportable operating segments. The company was formed to develop a polymer alternative to polyethylene glycol for pharmaceutical applications. Its website is https://serinatx.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
HUNTSVILLE, AL
Fiscal year end
December
CIK
1708599
SIC
2834

Financial performance, year by year

Fiscal 2018–2025 · USD
$-23.49M$-16.57M$-9.66M$-2.74M$4.17M20182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Serina Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

6
funds hold it
0 of 35
superinvestors hold it
$0.41M
held by funds, at market
0.8%
of shares held by funds

Largest fund holders · Serina Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
—of fund net assets
Ultra-Small Company Market Fund
BRSIX · Bridgeway Funds, Inc.
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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