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Companies / Health Care / Simulations Plus, Inc.
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Simulations Plus, Inc.

Health CareBusiness Services & SoftwareDeregistered 2026-10-16
Ticker —DURHAM, NCFiscal year ends AugustBook value per share $6.87Diluted shares 20.2M

Simulations Plus, Inc. provides software and consulting services for drug discovery, development, clinical trial operations, and commercialization. Its modeling and simulation tools help pharmaceutical, biotechnology, agrochemical, cosmetics, and food companies, as well as academic and regulatory organizations, assess… From the company’s description.

Over the twelve months to May 31, 2026, Simulations Plus, Inc. reported revenue of $82.06M, up 2.1% from a year earlier, and net income of $8.11M. Its operating margin was 14.0%, and operations generated $24.94M in cash. In fiscal 2025, it reported revenue of $79.18M, up 13.1% from fiscal 2024, and a net loss of $64.72M.

Fiscal year 2025 · ends 08-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-05-31
Sales & profitability
$79.18MFY2025
+13.1% year over year
Last 12 mo $82.06M
-89.33%FY2025
−98.1 percentage points
Last 12 mo 14.02%
$-64.72MFY2025
−750.2% year over year
Last 12 mo $8.11M
14.17%FY2025
+8.7 percentage points
Last 12 mo 5.83%
Cash & financing
$18.13MFY2025
+36.1% year over year
Last 12 mo $24.94M
$14.78MFY2025
+54.6% year over year
Last 12 mo $21.68M
—
20.1MFY2025
−1.0% year over year
Last 12 mo 20.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Simulations Plus, Inc. does

In the company’s own words

Simulations Plus, Inc. provides software and consulting services for drug discovery, development, clinical trial operations, and commercialization. Its modeling and simulation tools help pharmaceutical, biotechnology, agrochemical, cosmetics, and food companies, as well as academic and regulatory organizations, assess drug properties, inform dosing and formulation, design clinical trials, and support regulatory submissions and product launches. Software includes ADMET Predictor for AI- and machine-learning-based molecular property predictions, GastroPlus for drug absorption and pharmacokinetic simulations, DILIsym for liver-injury modeling, MonolixSuite for population modeling and clinical trial simulation, and Pro-ficiency for clinical trial training. Consulting spans pharmacokinetic and pharmacodynamic, physiologically based pharmacokinetic, and quantitative systems pharmacology modeling, as well as clinical operations and medical communications. The company reports two principal revenue categories: software, which accounted for 58% of fiscal 2025 revenue, and services, which accounted for 42%. It employed 213 people as of August 31, 2025. Its website is www.simulations-plus.com.

Company details
Sector
Health Care
Industry (SIC)
Business Services & Software
Headquarters
DURHAM, NC
Fiscal year end
August
CIK
1023459
SIC
7373

Financial performance, year by year

Fiscal 2012–2025 · USD
$-79.40M$-35.36M$8.67M$52.70M$96.74M20122013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Simulations Plus, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

141
funds hold it
0 of 35
superinvestors hold it
$69.66M
held by funds, at market

Largest fund holders · Simulations Plus, Inc.’s weight in each

First Eagle Small Cap Opportunity Fund
FESRX · First Eagle Funds
—of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
TRIBUTARY SMALL COMPANY FUND
FOSCX · TRIBUTARY CAPITAL MANAGEMENT, LLC
0.83%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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