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Companies / Health Care / Skye Bioscience, Inc.
SKYE

Skye Bioscience, Inc.

Health CarePharmaceutical Preparations
Ticker SKYESAN DIEGO, CAFiscal year ends DecemberBook value per share $-0.01Diluted shares 39.7M

Skye Bioscience, Inc. (Nasdaq: SKYE) is a clinical-stage biotechnology company developing molecules that modulate G-protein-coupled receptors to treat obesity, overweight and metabolic disorders. Its lead candidate, nimacimab, is a humanized antibody that targets the cannabinoid receptor 1 (CB1) and is designed to… From the company’s description.

In fiscal 2025, Skye Bioscience, Inc. reported a net loss of $55.92M. Operations used $43.06M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
—
0.00%FY2025
$-55.92MFY2025
−110.5% year over year
Last 12 mo $-50.49M
-279.29%FY2025
−240.3 percentage points
Last 12 mo 10159.56%
Cash & financing
$-43.06MFY2025
−70.6% year over year
Last 12 mo $-38.81M
$-43.07MFY2025
−60.5% year over year
Last 12 mo $-38.81M
—
Was 0.00× a year earlier
Last 12 mo -0.29
39.7MFY2025
+8.7% year over year
Last 12 mo 39.7M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Skye Bioscience, Inc. does

In the company’s own words

Skye Bioscience, Inc. (Nasdaq: SKYE) is a clinical-stage biotechnology company developing molecules that modulate G-protein-coupled receptors to treat obesity, overweight and metabolic disorders. Its lead candidate, nimacimab, is a humanized antibody that targets the cannabinoid receptor 1 (CB1) and is designed to inhibit the receptor outside the brain. The company is evaluating nimacimab as a standalone treatment and in combination with incretin-based therapies such as semaglutide; its CBeyond Phase 2a study enrolled adults with obesity or overweight. Skye operates as a single business focused on research and development, with no reportable segments described. It acquired nimacimab through its August 2023 acquisition of Bird Rock Bio. The company relies on third-party manufacturers to supply the candidate for preclinical and clinical studies, and its portfolio centers on nimacimab. In fiscal 2025, Skye reported no commercial product business and continued clinical development of its candidate. Its website is https://www.skyebioscience.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
SAN DIEGO, CA
Fiscal year end
December
CIK
1516551
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-61.62M$-44.53M$-27.44M$-10.34M$6.75M20132013201420152016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Skye Bioscience, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

7
funds hold it
0 of 35
superinvestors hold it
$0.69M
held by funds, at market
2.7%
of shares held by funds

Largest fund holders · Skye Bioscience, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
Fidelity Total Market Index Fund
FSKAX · Fidelity Concord Street Trust
—of fund net assets
Fidelity Series Total Market Index Fund
FCFMX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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