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Companies / Health Care / Surrozen, Inc.
SRZN

Surrozen, Inc.

Health CareBiological Products
Ticker SRZNSOUTH SAN FRANCISCO, CAFiscal year ends DecemberBook value per share $-19.34Diluted shares 11.3M

Surrozen, Inc. (Nasdaq: SRZN) is a biotechnology company discovering and developing antibody-based therapeutics that selectively modulate the Wnt signaling pathway, which is involved in tissue repair and regeneration. Its current focus is ophthalmology, developing treatments for retinal diseases including diabetic… From the company’s description.

In fiscal 2025, Surrozen, Inc. reported revenue of $3.48M, down 67.4% from fiscal 2024, and a net loss of $242.03M. Operations used $30.24M in cash. Over the twelve months to Jun 30, 2026, revenue was $11.51M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$3.48MFY2025
−67.4% year over year
Last 12 mo $11.51M
-1210.58%FY2025
−970.9 percentage points
Last 12 mo -385.28%
$-242.03MFY2025
−280.8% year over year
Last 12 mo $-332.13M
128.90%FY2025
−168.4 percentage points
Last 12 mo 151.89%
Cash & financing
$-30.24MFY2025
−71.6% year over year
Last 12 mo $-34.76M
$-30.37MFY2025
−72.0% year over year
Last 12 mo $-34.98M
—
7.5MFY2025
+155.0% year over year
Last 12 mo 11.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Surrozen, Inc. does

In the company’s own words

Surrozen, Inc. (Nasdaq: SRZN) is a biotechnology company discovering and developing antibody-based therapeutics that selectively modulate the Wnt signaling pathway, which is involved in tissue repair and regeneration. Its current focus is ophthalmology, developing treatments for retinal diseases including diabetic macular edema, wet age-related macular degeneration and uveitic macular edema. Its lead candidates include SZN-8141, which combines Fzd4 agonism with VEGF antagonism, and SZN-8143, which adds IL-6 antagonism; research programs also target retinal and corneal diseases. Surrozen’s SWAP platform designs multispecific antibodies to activate Wnt signaling through selected receptors. The company has one collaboration with Boehringer Ingelheim covering Fzd4 bispecific antibodies, including SZN-413, which Boehringer Ingelheim is responsible for developing, manufacturing and commercializing. Surrozen discontinued development of its liver-focused candidate SZN-043 in 2025 and has no commercialized products described here. It also conducts antibody discovery research for TCGFB targeting TGF-β. Its website is www.surrozen.com.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
SOUTH SAN FRANCISCO, CA
Fiscal year end
December
CIK
1824893
SIC
2836

Financial performance, year by year

Fiscal 2021–2025 · USD
$-366.59M$-263.20M$-159.81M$-56.43M$46.96M20212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Surrozen, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

47
funds hold it
0 of 35
superinvestors hold it
$19.66M
held by funds, at market
6.4%
of shares held by funds

Largest fund holders · Surrozen, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
0.01%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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