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Companies / Health Care / Tenax Therapeutics, Inc.
TENX

Tenax Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker TENXCHAPEL HILL, NCFiscal year ends DecemberBook value per share $2.18Diluted shares 49.9M

Tenax Therapeutics, Inc. (Nasdaq: TENX) is a development-stage pharmaceutical company developing therapies for cardiopulmonary diseases. Its prioritized candidate is oral levosimendan, being evaluated in two Phase 3 trials for pulmonary hypertension associated with heart failure with preserved ejection fraction… From the company’s description.

In fiscal 2025, Tenax Therapeutics, Inc. reported a net loss of $52.60M. Operations used $35.80M in cash.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
—
0.00%FY2025
$-52.60MFY2025
−198.8% year over year
Last 12 mo $-65.76M
-54.19%FY2025
−35.1 percentage points
Last 12 mo -60.52%
Cash & financing
$-35.80MFY2025
−141.7% year over year
Last 12 mo $-49.35M
$-35.80MFY2025
−141.7% year over year
Last 12 mo $-49.35M
—
Was 0.00× a year earlier
39.2MFY2025
+156.8% year over year
Last 12 mo 49.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Tenax Therapeutics, Inc. does

In the company’s own words

Tenax Therapeutics, Inc. (Nasdaq: TENX) is a development-stage pharmaceutical company developing therapies for cardiopulmonary diseases. Its prioritized candidate is oral levosimendan, being evaluated in two Phase 3 trials for pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF), a condition with no approved therapies. The company also has TNX-201, a modified-release formulation of imatinib under development for pulmonary arterial hypertension, although its Phase 3 program is currently deprioritized. Levosimendan is approved in many countries for acute decompensated heart failure, while imatinib is approved for other indications, including chronic myeloid leukemia. Tenax licenses levosimendan rights from Orion Corporation and contracts with third parties to manufacture its drug candidates and conduct clinical studies. It operates as a single development-stage pharmaceutical business, with no reportable segments described. As of December 31, 2025, Tenax had 14 full-time and two part-time employees. The company was renamed Tenax Therapeutics in 2014 as it began focusing on levosimendan. Its website is www.tenaxthera.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
CHAPEL HILL, NC
Fiscal year end
December
CIK
34956
SIC
2834

Financial performance, year by year

Fiscal 2011–2025 · USD
$-73.91M$-49.47M$-25.03M$-0.58M$23.86M20112012201320142016201720182019202020212022202320242025Last 12 moLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Tenax Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

73
funds hold it
0 of 35
superinvestors hold it
$52.74M
held by funds, at market
8.1%
of shares held by funds

Largest fund holders · Tenax Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
T. Rowe Price Health Sciences Fund, Inc.
PRHSX · T. ROWE PRICE HEALTH SCIENCES FUND, INC.
0.05%of fund net assets
Fidelity Advisor Biotechnology Fund
FBTAX · Fidelity Advisor Series VII
—of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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