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Companies / Health Care / TScan Therapeutics, Inc.
TCRX

TScan Therapeutics, Inc.

Health CareBiological Products
Ticker TCRXWALTHAM, MAFiscal year ends DecemberBook value per share $0.53Diluted shares 129.9M

TScan Therapeutics, Inc. (Nasdaq: TCRX) is a clinical-stage biotechnology company developing T cell receptor-engineered T cell (TCR-T) therapies for cancer and autoimmune disorders. Its lead candidate, TSC-101, is being studied for patients with acute myeloid leukemia and myelodysplastic syndrome undergoing allogeneic… From the company’s description.

Over the twelve months to Jun 30, 2026, TScan Therapeutics, Inc. reported revenue of $7.11M, up 2.2% from a year earlier, and a net loss of $117.71M. Operations used $116.28M in cash. In fiscal 2025, it reported revenue of $10.32M, up 266.7% from fiscal 2024, and a net loss of $129.77M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$10.32MFY2025
+266.7% year over year
Last 12 mo $7.11M
-1315.38%FY2025
+3472.3 percentage points
Last 12 mo -1695.15%
$-129.77MFY2025
−1.8% year over year
Last 12 mo $-117.71M
-105.40%FY2025
−52.5 percentage points
Last 12 mo -170.55%
Cash & financing
$-135.32MFY2025
−22.1% year over year
Last 12 mo $-116.28M
$-139.73MFY2025
−21.9% year over year
Last 12 mo $-118.44M
0.26FY2025
Was 0.13× a year earlier
Last 12 mo 0.47
129.8MFY2025
+15.9% year over year
Last 12 mo 129.9M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What TScan Therapeutics, Inc. does

In the company’s own words

TScan Therapeutics, Inc. (Nasdaq: TCRX) is a clinical-stage biotechnology company developing T cell receptor-engineered T cell (TCR-T) therapies for cancer and autoimmune disorders. Its lead candidate, TSC-101, is being studied for patients with acute myeloid leukemia and myelodysplastic syndrome undergoing allogeneic hematopoietic cell transplantation, with the goal of eliminating residual disease and preventing relapse. The company is developing additional blood-cancer candidates targeting CD45, as well as therapies for solid tumors that combine TCRs selected according to each patient’s tumor targets; its initial solid-tumor targets include HPV16, MAGE-A4 and PRAME. It is also researching potential treatments for ankylosing spondylitis, ulcerative colitis and scleroderma, and collaborates with Amgen on target discovery for Crohn’s disease. TScan operates an internal good manufacturing practices facility and uses a non-viral system to engineer T cells. In 2025, 42 patients had enrolled in its Phase 1 ALLOHA trial and undergone transplantation.

Company details
Sector
Health Care
Industry (SIC)
Biological Products
Headquarters
WALTHAM, MA
Fiscal year end
December
CIK
1783328
SIC
2836

Financial performance, year by year

Fiscal 2021–2025 · USD
$-144.85M$-99.60M$-54.36M$-9.11M$36.13M20212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns TScan Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

21
funds hold it
0 of 35
superinvestors hold it
$3.52M
held by funds, at market

Largest fund holders · TScan Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
0.04%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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