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Companies / Healthcare / Voyager Therapeutics, Inc.
VYGR

Voyager Therapeutics, Inc.

HealthcareBiological Products
Ticker VYGRLEXINGTON, MAFiscal year ends DecemberBook value per share $2.57Diluted shares 60.0M

Voyager Therapeutics, Inc. (NASDAQ: VYGR) is a biotechnology company focused on developing genetic medicines and other advanced therapeutics to treat neurological diseases. The company's mission centers on leveraging human genetics to modify the course of and ultimately cure neurological conditions affecting the… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$40.37M
−49.5% year over year
Last 12 mo $34.46M
-326.56%
−222.4 percentage points
Last 12 mo -340.08%
$-119.72M
−84.2% year over year
Last 12 mo $-107.73M
-61.06%
−39.4 percentage points
Last 12 mo -69.78%
Cash & financing
$-132.47M
−765.2% year over year
Last 12 mo $-120.57M
$-135.06M
−617.2% year over year
Last 12 mo $-121.42M
—
58.7M
+1.8% year over year
Last 12 mo 60.0M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Voyager Therapeutics, Inc. does

In the company’s own words

Voyager Therapeutics, Inc. (NASDAQ: VYGR) is a biotechnology company focused on developing genetic medicines and other advanced therapeutics to treat neurological diseases. The company's mission centers on leveraging human genetics to modify the course of and ultimately cure neurological conditions affecting the central nervous system.

The company operates through a portfolio of wholly-owned programs and collaborative partnerships. Its proprietary pipeline prioritizes Alzheimer's disease treatment, featuring two tau-targeting programs: VY1706, a tau silencing gene therapy delivered intravenously using a TRACER capsid containing vectorized small interfering RNA, and VY7523, an anti-tau monoclonal antibody currently in Phase 1 clinical trials. Voyager is also developing a non-viral therapeutic leveraging its proprietary Voyager NeuroShuttle platform for undisclosed neurological diseases.

The company's core technology platform, TRACER (Tropism Redirection of AAV by Cell-type-specific Expression of RNA), enables discovery of adeno-associated virus capsids with robust blood-brain-barrier penetration and enhanced central nervous system tropism. This platform has generated novel capsids and identified associated receptors to facilitate high brain penetration through intravenous dosing. The Voyager NeuroShuttle platform represents a non-viral delivery system leveraging receptor-binding molecules to transport neurotherapeutics across the blood-brain barrier.

Beyond wholly-owned programs, Voyager maintains collaborative relationships with major pharmaceutical partners including Neurocrine Biosciences, Novartis Pharma AG, and Alexion, AstraZeneca Rare Disease. These partnerships address conditions including Friedreich's ataxia, Gaucher disease, Parkinson's disease, spinal muscular atrophy, and Huntington's disease. Collaborations have delivered over $500 million in non-dilutive funding to date, with potential future milestone payments reaching $6.8 billion across the partnered portfolio.

The company also maintains an option agreement with Transition Bio to develop selective small molecules targeting TDP-43 for amyotrophic lateral sclerosis and frontotemporal dementia treatment. Voyager's website is located at www.voyagertherapeutics.com.

Company details
Sector
Healthcare
Industry
Biological Products
Headquarters
LEXINGTON, MA
Fiscal year end
December
CIK
1640266
SIC
2836

Financial performance, year by year

Fiscal 2015–2025 · USD
$-156.69M$-45.78M$65.14M$176.06M$286.98M20152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Voyager Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

127
funds hold it
0 of 35
superinvestors hold it
$33.31M
held by funds, at market
15.0%
of shares held by funds

Largest fund holders · Voyager Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.01%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 Value ETF
IWN · iShares Trust
0.01%of fund net assets
Fidelity Small Cap Index Fund
FSSNX · Fidelity Salem Street Trust
0.01%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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