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Companies / Health Care / Coya Therapeutics, Inc.
COYA

Coya Therapeutics, Inc.

Health CarePharmaceutical Preparations
Ticker COYAHOUSTON, TXFiscal year ends DecemberBook value per share $1.88Diluted shares 23.1M

Coya Therapeutics, Inc. (Nasdaq: COYA) is a clinical-stage biotechnology company developing therapies intended to enhance regulatory T-cell (Treg) function for neurodegenerative, autoimmune and metabolic diseases. Its approaches include Treg-enhancing biologics, Treg-derived exosomes and autologous Treg cell therapy;… From the company’s description.

Over the twelve months to Jun 30, 2026, Coya Therapeutics, Inc. reported revenue of $8.02M, up 1791.3% from a year earlier, and a net loss of $21.67M. Its operating margin was −288.7%, and operations used $15.72M in cash. In fiscal 2025, it reported revenue of $7.95M, up 123.6% from fiscal 2024, and a net loss of $21.23M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$7.95MFY2025
+123.6% year over year
Last 12 mo $8.02M
-283.87%FY2025
+201.5 percentage points
Last 12 mo -288.70%
$-21.23MFY2025
−42.6% year over year
Last 12 mo $-21.67M
-49.33%FY2025
−11.7 percentage points
Last 12 mo -50.07%
Cash & financing
$-10.74MFY2025
−4.4% year over year
Last 12 mo $-15.72M
$-10.74MFY2025
−4.4% year over year
Last 12 mo $-15.72M
—
16.7MFY2025
+9.8% year over year
Last 12 mo 23.1M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Coya Therapeutics, Inc. does

In the company’s own words

Coya Therapeutics, Inc. (Nasdaq: COYA) is a clinical-stage biotechnology company developing therapies intended to enhance regulatory T-cell (Treg) function for neurodegenerative, autoimmune and metabolic diseases. Its approaches include Treg-enhancing biologics, Treg-derived exosomes and autologous Treg cell therapy; it has no commercial products described. Its leading candidate, COYA 302, combines low-dose interleukin-2 (COYA 301) with CTLA4-Ig and is being studied in a Phase 2 trial for amyotrophic lateral sclerosis (ALS); the company is also planning clinical development for frontotemporal dementia. COYA 303 combines COYA 301 with a GLP-1 receptor agonist and remains in preclinical development. COYA 301 is also being developed as a potential standalone therapy and as the backbone for combination treatments. The company’s exosome programs include COYA 201, an allogeneic Treg-derived candidate in preclinical development. Coya has completed Phase 1 and Phase 2a studies of autologous Treg cell therapy in ALS. Its operations focus on research and development, funded primarily through securities sales.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
HOUSTON, TX
Fiscal year end
December
CIK
1835022
SIC
2834

Financial performance, year by year

Fiscal 2022–2025 · USD
$-24.64M$-15.73M$-6.82M$2.08M$10.99M2022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Coya Therapeutics, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

20
funds hold it
1 of 35
superinvestors hold it
$6.74M
held by funds, at market
5.2%
of shares held by funds

Superinvestors in Coya Therapeutics, Inc. · what they did last quarter

David EinhornUNCHANGED
DME Capital Management (Greenlight)
0.3%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Coya Therapeutics, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.00%of fund net assets
Fidelity Extended Market Index Fund
FSMAX · Fidelity Concord Street Trust
—of fund net assets
iShares Micro-Cap ETF
IWC · iShares Trust
0.03%of fund net assets
Dimensional U.S. Small Cap ETF
DFAS · Dimensional ETF Trust
—of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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