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Companies / Healthcare / EyePoint, Inc.
EYPT

EyePoint, Inc.

HealthcareMedical Instruments
Ticker EYPTWATERTOWN, MAFiscal year ends DecemberBook value per share $1.93Diluted shares 86.3M

EyePoint Pharmaceuticals, Inc. (Nasdaq: EYPT) is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapeutics for serious retinal diseases. The company leverages its proprietary bioerodible Durasert E technology platform for sustained intraocular drug delivery, enabling… From the company’s description.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$31.37M
−27.5% year over year
Last 12 mo $2.79M
-775.98%
−438.9 percentage points
Last 12 mo -11369.30%
$-231.96M
−77.2% year over year
Last 12 mo $-306.64M
-75.78%
−36.9 percentage points
Last 12 mo -184.27%
Cash & financing
$-240.11M
−90.2% year over year
Last 12 mo $-267.30M
$-243.39M
−86.8% year over year
Last 12 mo $-271.28M
—
73.3M
+30.1% year over year
Last 12 mo 86.3M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What EyePoint, Inc. does

In the company’s own words

EyePoint Pharmaceuticals, Inc. (Nasdaq: EYPT) is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapeutics for serious retinal diseases. The company leverages its proprietary bioerodible Durasert E technology platform for sustained intraocular drug delivery, enabling consistent therapeutic release over extended periods through a single intravitreal injection administered in a physician's office.

The company's lead product candidate, DURAVYU, combines vorolanib, a selective tyrosine kinase inhibitor, with the Durasert E delivery system to target vascular endothelial growth factor-mediated retinal diseases. DURAVYU is currently in Phase 3 pivotal trials for wet age-related macular degeneration and diabetic macular edema, representing the two largest retinal disease markets. The company completed enrollment in its wet AMD Phase 3 trials, LUGANO and LUCIA, with topline data anticipated in mid-2026. The first patient was dosed in the Phase 3 DME program in February 2026. The company's pipeline also includes EYP-2301, razuprotafib formulated in Durasert E, in preclinical development for serious retinal diseases.

EyePoint's Durasert technology has been safely administered to thousands of patient eyes across four FDA-approved products. The bioerodible Durasert E formulation allows for higher drug payload delivery with complete bioabsorption, eliminating the need for surgical removal. Vorolanib's multi-mechanism of action addresses vascular permeability through VEGF receptor inhibition while providing anti-inflammatory effects through IL-6 and JAK-1 pathway inhibition, differentiating DURAVYU from existing anti-VEGF ligand-blocking therapies.

The company maintains manufacturing facilities in Watertown and Northbridge, Massachusetts, with a state-of-the-art facility in Northbridge supporting potential commercial launch preparations. EyePoint has established licensing agreements with Equinox Science for vorolanib intellectual property and with Betta Pharmaceuticals for Greater China commercialization rights. The company reported cash, cash equivalents, and marketable securities of $306.1 million as of December 31, 2025, providing funding runway into the fourth quarter of 2027. More information is available at www.eyepointpharma.com.

Company details
Sector
Healthcare
Industry
Medical Instruments
Headquarters
WATERTOWN, MA
Fiscal year end
December
CIK
1314102
SIC
3826

Financial performance, year by year

Fiscal 2014–2025 · USD
$-341.91M$-236.11M$-130.31M$-24.51M$81.28M2014201520162017201820182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns EyePoint, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

166
funds hold it
0 of 35
superinvestors hold it
$351.23M
held by funds, at market
29.6%
of shares held by funds

Largest fund holders · EyePoint, Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
Federated Hermes Kaufmann Fund
KAUAX · Federated Hermes Equity Funds
0.78%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.03%of fund net assets
Federated Hermes Kaufmann Small Cap Fund
FKASX · Federated Hermes Equity Funds
0.91%of fund net assets
Franklin Small Cap Growth Fund
FSGRX · Franklin Strategic Series
0.81%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

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