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Companies / Health Care / Immunome Inc.
IMNM

Immunome Inc.

Health CarePharmaceutical Preparations
Ticker IMNMBOTHELL, WAFiscal year ends DecemberBook value per share $4.64Diluted shares 113.2M

Immunome, Inc. (Nasdaq: IMNM) is a biotechnology company developing targeted therapies for cancer, including antibody-drug conjugates (ADCs) and radioligand therapies. Its pipeline includes three clinical-stage and three preclinical assets. Varegacestat, an oral gamma secretase inhibitor acquired from Ayala… From the company’s description.

In fiscal 2025, Immunome Inc. reported revenue of $6.94M, down 23.2% from fiscal 2024, and a net loss of $212.39M. Its operating margin was −3228.8%, and operations used $190.92M in cash. Over the twelve months to Jun 30, 2026, revenue was $0.00M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$6.94MFY2025
−23.2% year over year
Last 12 mo $0.00M
-3228.83%FY2025
+153.5 percentage points
$-212.39MFY2025
+27.5% year over year
Last 12 mo $-254.32M
-33.48%FY2025
+128.2 percentage points
Last 12 mo -48.43%
Cash & financing
$-190.92MFY2025
−72.3% year over year
Last 12 mo $-208.79M
$-200.60MFY2025
−70.1% year over year
Last 12 mo $-219.09M
—
87.4MFY2025
+49.0% year over year
Last 12 mo 113.2M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Immunome Inc. does

In the company’s own words

Immunome, Inc. (Nasdaq: IMNM) is a biotechnology company developing targeted therapies for cancer, including antibody-drug conjugates (ADCs) and radioligand therapies. Its pipeline includes three clinical-stage and three preclinical assets. Varegacestat, an oral gamma secretase inhibitor acquired from Ayala Pharmaceuticals in 2024, is being developed for desmoid tumors; the company reported positive Phase 3 results in 2025 and is preparing a regulatory submission. IM-1021 is a ROR1-targeted ADC in a Phase 1 trial for solid tumors and B-cell lymphomas, while IM-3050 is a FAP-targeted radioligand therapy planned for Phase 1 evaluation. The company’s preclinical pipeline includes three solid-tumor ADCs, IM-1617, IM-1340 and IM-1335, and additional early-stage ADC programs. Its ADC research uses proprietary HC74, a topoisomerase 1 inhibitor payload, and focuses on novel or underexplored targets. Immunome’s operations center on discovering and developing oncology medicines, with potential commercialization of its products also part of its strategy.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BOTHELL, WA
Fiscal year end
December
CIK
1472012
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-323.66M$-231.57M$-139.47M$-47.38M$44.72M202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Immunome Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

211
funds hold it
0 of 35
superinvestors hold it
$1.16B
held by funds, at market
47.0%
of shares held by funds

Largest fund holders · Immunome Inc.’s weight in each

T. Rowe Price Small-Cap Stock Fund, Inc.
OTCFX · T. ROWE PRICE SMALL-CAP STOCK FUND, INC.
1.64%of fund net assets
Fidelity Growth Company Fund
FDGRX · Fidelity Mt. Vernon Street Trust
0.10%of fund net assets
PRIMECAP Odyssey Aggressive Growth Fund
POAGX · PRIMECAP Odyssey Funds
—of fund net assets
T. Rowe Price Institutional Small-Cap Stock Fund
TRSSX · T. Rowe Price Equity Funds, Inc.
1.65%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Immunome Inc. and its peers compare on margins and cash generation over ten years?”
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