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Companies / Health Care / INSMED Inc
INSM

INSMED Inc

Health CarePharmaceutical Preparations
Ticker INSMBRIDGEWATER, NJFiscal year ends DecemberBook value per share $3.50Diluted shares 216.4M

Insmed Incorporated (Nasdaq: INSM) is a biopharmaceutical company that develops and commercializes therapies for serious diseases, with commercial products and a clinical pipeline across Respiratory, Immunology & Inflammation, and Neuro & Other Rare. Its marketed respiratory products are ARIKAYCE, an inhaled amikacin… From the company’s description.

In fiscal 2025, INSMED Inc reported revenue of $606.42M, up 66.7% from fiscal 2024, and a net loss of $1.28B. Its operating margin was −205.6%, and operations used $935.01M in cash. Over the twelve months to Jun 30, 2026, revenue was $1.14B.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$606.42MFY2025
+66.7% year over year
Last 12 mo $1.14B
-205.59%FY2025
+35.9 percentage points
Last 12 mo -73.89%
$-1.28BFY2025
−39.7% year over year
Last 12 mo $-875.31M
-172.78%FY2025
+147.4 percentage points
Last 12 mo -115.55%
Cash & financing
$-935.01MFY2025
−36.7% year over year
Last 12 mo $-778.92M
$-967.58MFY2025
−37.1% year over year
Last 12 mo $-807.67M
0.76FY2025
Was 3.96× a year earlier
Last 12 mo 0.75
199.0MFY2025
+21.3% year over year
Last 12 mo 216.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What INSMED Inc does

In the company’s own words

Insmed Incorporated (Nasdaq: INSM) is a biopharmaceutical company that develops and commercializes therapies for serious diseases, with commercial products and a clinical pipeline across Respiratory, Immunology & Inflammation, and Neuro & Other Rare. Its marketed respiratory products are ARIKAYCE, an inhaled amikacin treatment for certain adults with Mycobacterium avium complex lung disease, and BRINSUPRI, an oral treatment for non-cystic fibrosis bronchiectasis in patients 12 and older. The respiratory pipeline includes inhaled treprostinil palmitil (TPIP) and the antibody INS1148; brensocatib is also in development for hidradenitis suppurativa, while gene therapy candidates INS1201 and INS1202 target Duchenne muscular dystrophy and amyotrophic lateral sclerosis. The company’s preclinical research uses gene therapy, protein engineering, RNA end-joining, and other technologies. Insmed reports its business through three therapeutic areas rather than revenue-reporting segments. It licenses and acquires products and candidates, including brensocatib from AstraZeneca and INS1148 from Opsidio, and relies on external manufacturers for commercial and clinical supply. Its website is https://www.insmed.com/.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
BRIDGEWATER, NJ
Fiscal year end
December
CIK
1104506
SIC
2834

Financial performance, year by year

Fiscal 2013–2025 · USD
$-1.52B$-793.89M$-69.57M$654.75M$1.38B2013201420152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns INSMED Inc — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

660
funds hold it
1 of 35
superinvestors hold it
$9.27B
held by funds, at market
38.4%
of shares held by funds

Superinvestors in INSMED Inc · what they did last quarter

Stanley DruckenmillerINCREASED +23.4%
Duquesne Family Office
3.5%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · INSMED Inc’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.03%of fund net assets
0.19%of fund net assets
JPMorgan Large Cap Growth Fund
SEEGX · JPMorgan Trust II
0.24%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.14%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.27%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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