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Companies / Health Care / Natera, Inc.
NTRA

Natera, Inc.

Health CareHealth Services
Ticker NTRAAUSTIN, TXFiscal year ends DecemberBook value per share $12.79Diluted shares 142.4M

Natera, Inc. (Nasdaq: NTRA) is a diagnostics company that applies proprietary molecular assays and bioinformatics to genetic testing in oncology, women’s health and organ health. Its products include Signatera, a personalized blood test for cancer residual disease and recurrence monitoring; Panorama, a non-invasive… From the company’s description.

In fiscal 2025, Natera, Inc. reported revenue of $2.31B, up 35.9% from fiscal 2024, and a net loss of $208.16M. Its operating margin was −13.4%, and operations generated $215.30M in cash. Over the twelve months to Jun 30, 2026, revenue was $2.71B.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$2.31BFY2025
+35.9% year over year
Last 12 mo $2.71B
-13.44%FY2025
−0.3 percentage points
Last 12 mo -10.70%
$-208.16MFY2025
−9.3% year over year
Last 12 mo $-192.35M
-12.16%FY2025
+3.8 percentage points
Last 12 mo -10.56%
Cash & financing
$215.30MFY2025
+58.7% year over year
Last 12 mo $228.24M
$109.11MFY2025
+57.6% year over year
Last 12 mo $84.20M
0.05FY2025
Was 0.07× a year earlier
Last 12 mo 0.04
136.7MFY2025
+9.6% year over year
Last 12 mo 142.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Natera, Inc. does

In the company’s own words

Natera, Inc. (Nasdaq: NTRA) is a diagnostics company that applies proprietary molecular assays and bioinformatics to genetic testing in oncology, women’s health and organ health. Its products include Signatera, a personalized blood test for cancer residual disease and recurrence monitoring; Panorama, a non-invasive prenatal screen; Horizon, a carrier screening test; and Prospera, which assesses rejection after kidney, heart and lung transplants. Other offerings include tumor profiling, hereditary cancer and single-gene screening, kidney disease testing, and Constellation, cloud software that lets partner laboratories run testing workflows and analyze results using Natera’s algorithms. Customers and users include healthcare providers, laboratories, researchers and biopharmaceutical companies; tests are sold directly in the United States and through laboratory and distribution partners internationally. Natera reports three medical areas of focus—oncology, women’s health and organ health—and processes tests in its own CLIA-certified laboratories. In 2025, revenue was $2.31 billion, and the company processed approximately 3.5 million tests. Its website is www.natera.com.

Company details
Sector
Health Care
Industry (SIC)
Health Services
Headquarters
AUSTIN, TX
Fiscal year end
December
CIK
1604821
SIC
8071

Financial performance, year by year

Fiscal 2015–2025 · USD
$-873.29M$103.18M$1.08B$2.06B$3.03B20152016201720182019202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Natera, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

684
funds hold it
2 of 35
superinvestors hold it
$14.88B
held by funds, at market
41.1%
of shares held by funds

Superinvestors in Natera, Inc. · what they did last quarter

Stanley DruckenmillerINCREASED +4.0%
Duquesne Family Office
19.9%of 13F portfolio
Polen CapitalINCREASED +28.2%
Polen Capital Management
<0.1%of 13F portfolio

Share of each manager’s reported 13F portfolio. Change is in shares held, since the previous quarter.

Largest fund holders · Natera, Inc.’s weight in each

JPMorgan Large Cap Growth Fund
SEEGX · JPMorgan Trust II
1.24%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.05%of fund net assets
VANGUARD SMALL-CAP INDEX FUND
VB · VANGUARD INDEX FUNDS
0.45%of fund net assets
VANGUARD SMALL-CAP GROWTH INDEX FUND
VBK · VANGUARD INDEX FUNDS
1.04%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.46%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Fund ownership is a subset of institutional 13F ownership — the two describe overlapping populations and must not be added together.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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