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Companies / Health Care / Shattuck Labs, Inc.
STTK

Shattuck Labs, Inc.

Health CarePharmaceutical Preparations
Ticker STTKAUSTIN, TXFiscal year ends DecemberBook value per share $1.36Diluted shares 142.4M

Shattuck Labs, Inc. (Nasdaq: STTK) is a clinical-stage biotechnology company developing monoclonal and bispecific antibodies for inflammatory and immune-mediated diseases. Its lead candidate, SL-325, is a DR3-blocking antibody being evaluated for inflammatory bowel disease, initially Crohn’s disease; the company is… From the company’s description.

Over the twelve months to Sep 30, 2026, Shattuck Labs, Inc. reported a net loss of $67.72M. Operations used $49.57M in cash. In fiscal 2025, it reported revenue of $1.00M, down 82.5% from fiscal 2024, and a net loss of $48.81M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-09-30
Sales & profitability
$1.00MFY2025
−82.5% year over year
Last 12 mo $0.00M
-5150.80%FY2025
−3742.5 percentage points
$-48.81MFY2025
+35.3% year over year
Last 12 mo $-67.72M
-59.24%FY2025
+35.5 percentage points
Last 12 mo -34.97%
Cash & financing
$-39.88MFY2025
+34.1% year over year
Last 12 mo $-49.57M
$-39.95MFY2025
+34.0% year over year
Last 12 mo $-49.76M
—
69.6MFY2025
+37.1% year over year
Last 12 mo 142.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Shattuck Labs, Inc. does

In the company’s own words

Shattuck Labs, Inc. (Nasdaq: STTK) is a clinical-stage biotechnology company developing monoclonal and bispecific antibodies for inflammatory and immune-mediated diseases. Its lead candidate, SL-325, is a DR3-blocking antibody being evaluated for inflammatory bowel disease, initially Crohn’s disease; the company is conducting a Phase 1 trial in healthy volunteers and plans a Phase 2 trial in patients. Shattuck is also developing SL-425, a half-life-extended version of SL-325, and preclinical bispecific antibodies designed to target DR3 alongside other immune-disease targets. Its research draws on protein engineering and tumor necrosis factor receptor biology, and its candidates are investigational rather than marketed products. The company relies on third-party manufacturers for production of its drug candidates. Its website is https://www.shattucklabs.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
AUSTIN, TX
Fiscal year end
December
CIK
1680367
SIC
2834

Financial performance, year by year

Fiscal 2020–2025 · USD
$-115.14M$-75.55M$-35.96M$3.62M$43.21M202020212022202320242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Shattuck Labs, Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

93
funds hold it
0 of 35
superinvestors hold it
$138.64M
held by funds, at market
19.8%
of shares held by funds

Largest fund holders · Shattuck Labs, Inc.’s weight in each

T. Rowe Price Small-Cap Value Fund, Inc.
PRSVX · T. ROWE PRICE SMALL-CAP VALUE FUND, INC.
0.23%of fund net assets
T. Rowe Price Small-Cap Stock Fund, Inc.
OTCFX · T. ROWE PRICE SMALL-CAP STOCK FUND, INC.
0.23%of fund net assets
VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
T. Rowe Price Health Sciences Fund, Inc.
PRHSX · T. ROWE PRICE HEALTH SCIENCES FUND, INC.
0.12%of fund net assets
T. Rowe Price Institutional Small-Cap Stock Fund
TRSSX · T. Rowe Price Equity Funds, Inc.
0.23%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Fund ownership counts N-PORT filers only, so it is a floor rather than a census — pensions, insurers and direct holders are not visible here, and the remainder is not “held by individuals”.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

Put this business in context.

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  • “How do Shattuck Labs, Inc. and its peers compare on margins and cash generation over ten years?”
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