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Companies / Health Care / Alumis Inc.
ALMS

Alumis Inc.

Health CarePharmaceutical Preparations
Ticker ALMSSOUTH SAN FRANCISCO, CAFiscal year ends DecemberBook value per share $3.58Diluted shares 126.4M

Alumis Inc. (Nasdaq: ALMS) is a clinical-stage biopharmaceutical company developing targeted therapies for immune-mediated diseases. Its lead candidate, envudeucitinib (envu), is an allosteric TYK2 inhibitor being studied for plaque psoriasis and systemic lupus erythematosus; the company also develops A-005, a… From the company’s description.

In fiscal 2025, Alumis Inc. reported revenue of $24.05M and a net loss of $243.32M. Operations used $369.52M in cash. Over the twelve months to Jun 30, 2026, revenue was $7.40M.

Fiscal year 2025 · ends 12-31Changes are against fiscal 2024The amber dot is the latest twelve months, to 2026-06-30
Sales & profitability
$24.05MFY2025
Last 12 mo $7.40M
-1886.92%FY2025
Last 12 mo -6204.39%
$-243.32MFY2025
+17.3% year over year
Last 12 mo $-438.96M
-80.76%FY2025
+32.4 percentage points
Last 12 mo -97.08%
Cash & financing
$-369.52MFY2025
−44.9% year over year
Last 12 mo $-351.40M
$-370.18MFY2025
−44.1% year over year
Last 12 mo $-351.80M
—
85.0MFY2025
+200.0% year over year
Last 12 mo 126.4M

Margins and return on equity change in ; everything else in percent. Fewer shares and less debt are shown plainly, not as bad news — it depends what you make of buybacks. Dotted labels explain each measure. is shown separately from the annual figures.

What Alumis Inc. does

In the company’s own words

Alumis Inc. (Nasdaq: ALMS) is a clinical-stage biopharmaceutical company developing targeted therapies for immune-mediated diseases. Its lead candidate, envudeucitinib (envu), is an allosteric TYK2 inhibitor being studied for plaque psoriasis and systemic lupus erythematosus; the company also develops A-005, a CNS-penetrant TYK2 inhibitor for potential neurological and other indications. Its pipeline includes lonigutamab, a subcutaneous monoclonal antibody targeting IGF-1R for thyroid eye disease, acquired through the 2025 merger with ACELYRIN. Alumis also pursues earlier-stage discovery programs, including work on IRF5, using a precision data analytics platform to inform target and drug development. The company has no approved products or established commercial organization and relies on third parties to manufacture clinical supplies. Its website is https://alumis.com.

Company details
Sector
Health Care
Industry (SIC)
Pharmaceutical Preparations
Headquarters
SOUTH SAN FRANCISCO, CA
Fiscal year end
December
CIK
1847367
SIC
2834

Financial performance, year by year

Fiscal 2024–2025 · USD
$-485.26M$-346.36M$-207.45M$-68.55M$70.35M20242025Last 12 moLast 12 monthsLast 12 months

The full income statement, balance sheet and cash flow for each of these years — every figure traceable to its filing — is on the Financials tab with a free account.

Ownership

Who owns Alumis Inc. — and what changed

Funds as of 2026Q2 · superinvestors as of 2026-06-30

197
funds hold it
0 of 35
superinvestors hold it
$576.25M
held by funds, at market

Largest fund holders · Alumis Inc.’s weight in each

VANGUARD TOTAL STOCK MARKET INDEX FUND
VTI · VANGUARD INDEX FUNDS
0.00%of fund net assets
iShares Russell 2000 ETF
IWM · iShares Trust
0.07%of fund net assets
T. Rowe Price New Horizons Fund, Inc.
PRNHX · T. ROWE PRICE NEW HORIZONS FUND, INC.
0.26%of fund net assets
T. Rowe Price Integrated U.S. Small-Cap Growth Equity Fund
PRDSX · T. ROWE PRICE INTEGRATED EQUITY FUNDS, INC.
0.31%of fund net assets
VANGUARD EXTENDED MARKET INDEX FUND
VXF · VANGUARD INDEX FUNDS
0.03%of fund net assets

Fund ownership is a floor, not a census — pensions, insurers and people holding shares directly are not visible here.

Could not be determined for this company: bond issues.

Every fund and institutional holder, quarter by quarter, is on the Ownership tab with a free account.

Connected research

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