BlackRock Health Sciences Opportunities Portfolio

BlackRock Funds · 4 share classes

Actively managed U.S. equity fund
One fund, 4 share classes:SHSSXSHISXSHSAXSHSCX
$5.91B NAV
152 positions · as of 2026-05-29 · filed 2026-07-27

Fund classification

Classified from what the fund holds · as of 2026 Q2

BlackRock Health Sciences Opportunities Portfolio is an actively managed U.S. equity fund. 21% of SHSSX’s stock holdings are in companies whose revenue grew in the top quartile of U.S. companies over the last five fiscal years (covering 87% of the fund’s equity).

Asset class
Equity
Region
United States
Management
Actively managed
Fund type
Open-end fund

Fund profile

As filed in the prospectus · 2025 Q3

The investment objective of BlackRock Health Sciences Opportunities Portfolio (the Fund), a series of BlackRock Funds SM (the Trust), is to provide long-term growth of capital.

Strategy · summarised

The fund invests at least 80% of its assets in equity securities of companies in health sciences and related industries, including biotechnology, pharmaceuticals, medical equipment and supplies, health care providers, and diagnostic services. The fund concentrates more than 25% of its assets in the health sciences sector and may hold securities of non-U.S. companies. Up to 20% of assets may be invested in other equity securities outside health sciences.

Expenses
0.75% 1.85%across 6 share classes
Share classGrossNet
SHSSX0.84%0.84%
SHISX1.15%1.15%
SHSAX1.09%1.09%
SHSCX1.85%1.85%
C0000376611.45%1.44%
C0001729000.75%0.75%

Net is what a holder pays after the adviser's contractual waiver; gross is before it. A waiver can expire.

Portfolio turnover 43.00% · as of 2025 Q3

Allocation

Asset groups · long / short shown separately, never netted · 2026 Q2

101.14%
of net assets
Stocks99.77%
Cash & short-term1.37%
Other0.01%

Derivatives are shown at market value, not notional exposure.

Sector allocation

The same holdings as Allocation above, grouped by market sector instead of asset type · as of 2026 Q2

100%
of net assets
Health Care93.0%
International4.7%
Cash1.4%
Other1.0%

Government, Securitized and Cash are non-corporate buckets; International is foreign holdings we don’t sector-classify, and Other is the residual (held funds, unresolved names).

Portfolio growth profile

How much of the fund’s stock holdings are in fast-growing companies · as of 2026 Q2

Revenue growth
21%of stock holdings in top-quartile growers
covering 87% of the fund’s equity

Share of the fund’s equity (by value) in companies whose trailing five-year revenue — or net-income — growth ranks in the top 25% of U.S. public companies. Foreign and newly-listed holdings are excluded, so the figure covers only part of the book. From SEC filings — not investment advice. How we measure this.

Latest quarter

What changed since the fund's previous filing

2026Q2 vs 2026Q1: 16 new26 exited

Largest new: MDGL, KLRA, AXSM, PVLA, RLAY, AVTX, SGMT, BCAX

Largest exited: Medtronic PLC, Roche Holding AG, Exact Sciences Corporation, GH, CNC, COO, GEHC, VEEV

Return profile

Chart:

Total return as filed — price change plus distributions reinvested · trailing figures to Apr 2026

Share class1-year3-year5-yearVolWorst fall
+8.86%+18.17%+20.45%15.05%-13.37%
+8.50%+17.03%+18.66%15.05%-13.54%
+8.59%+17.30%+19.02%15.06%-13.53%
+7.73%+14.54%+14.51%15.05%-14.01%
+8.18%+16.00%+16.83%15.05%-13.75%
+8.95%+18.51%+21.08%15.06%-13.30%

These classes hold the same portfolio, so the 6.57pp spread over 5 years is the cost difference between them — roughly 1.31pp a year — not a difference in what they own.

Cumulative return· Jun 2023 – Apr 2026

May 2026 has been filed since the trailing figures were struck, so it is not in the table above or the curve — every figure here shares one cut-off, which is what makes them comparable with other funds.

Holdings

By % of NAV · equity positions carry filed share counts · every resolvable issuer links to its company page

Issuer%NAVValue
ELI LILLY & COMPANYLLY12.29%$725.60M
JOHNSON & JOHNSONJNJ8.77%$518.08M
UNITEDHEALTH GROUP INCUNH6.10%$360.31M
MERCK & COMPANY INCMRK4.94%$291.63M
GILEAD SCIENCES INCGILD4.19%$247.53M
ABBVIE INCABBV3.94%$232.53M
AMGEN INCAMGN3.37%$198.77M
THERMO FISHER SCIENTIFIC INCTMO3.02%$178.45M
VERTEX PHARMACEUTICALS INCVRTX2.74%$161.97M
PFIZER INCPFE2.62%$154.44M
Showing 10 of 152Sign in to see more

Reported price is the fund's own reported value divided by its own reported shares at 2026-05-29 — not a live quote, and not what the fund paid.

Top 10 positions are 51.97% of net assets, top 25 74.05%, across 150 issuers.

See more of this fund's book

More positions with filed share counts, and the quarter-over-quarter change list rather than the largest few — free with an account, no card required.

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